Ricky Duncan's team will include keeper Ian Joyce, winger Damien Scannell and striker James Walker, and they will join a mainly youthful line up at Peterborough this afternoon.
The match was originally meant to take place at Roots Hall but was changed last week.
Southend United: Joyce, Owinja, Whittaker, Reynolds, Osifuwa, Walker, O'Keefe, James-Lewis, Scannell, Calver, Asante.
Subs: Crawford, Milner, Dennis, Bentley.